After years of cancer research work in England and discovering novel human proteins involved in cancer progression, Dr. Mehrotra returned to India in 2012 to join The Centre for Chemical Biology and Therapeutics at National Centre for Biological Sciences, Bengaluru, India – a joint initiative of the University of Cambridge, United Kingdom and the Department of Biotechnology, Government of India. His work revolved around discovering new therapeutic interventions for breast cancer patients. As he visited the oncology OPDs, he noticed women wearing sarees draped (pallu in hindi) on either the right or the left side. This observation made him inquire an elderly couple about the reason for the same to understand the situation. Both the husband and wife with a white tika on their forehead were visibly tired of waiting for their turn. The wife did not talk at all and didn’t even establish an eye contact whereas the husband described that his wife had undergone a right unilateral mastectomy and had come for a follow up. With a voice full of pain, he explained that his wife is far more disturbed because of the permanent VOID which has been created in her body than she was during the whole surgical and subsequent treatment process. He said that though her wife is very religious but it was god’s will and that this has happened for the first time in their extended family. He concluded by making a powerful remark – “Why doesn’t the hospital provide a solution before/post removal of breast(s) so that patients can get rid of this physical and emotional turmoil?” – the comment stayed with Dr. Mehrotra and he developed a miraculous association with this issue of post-surgical rehabilitation of mastectomees. Subsequent conversations with breast cancer patients who had undergone mastectomy revealed the dire emotional & physical deprivation that haunts women after the loss of one or more breast(s) as part of the treatment and this reinforced his belief to do something about this unmet medical need.