CEFURIN-CV-625-TABLETS:
Cefuroxime Axetil I.P eq.to Anhydrous Cefuroxime 500 mg+Potassium Clavulanate Diluted I.P. eq. to Clavulanic Acid 125 mg
INDICATION:
Pneumonia
Bronchitis
Sinusitis
Cystitis
SSTI
UTI
Cefuroxime Axetil:
An oral prodrug of the bactericidal cefuroxime antibiotics.
Effective against wide range of gram positive and gram negative organisms including beta lactamase producing strains.
Clavulanic Acid:
Possess the distinctive properties of a broad spectrum antibiotics and β-lactamase inhibitor.
Protect cefuroxime from degradation by β-lactamase enzyme.
Effectively extends the spectrum to include many bacteria normally resistant to cefuroxime and other β-lactam antibiotic.
Combination of Cefuroxime and clavulanic acid provides a solution for treatment of bacterial infections caused by β-lactam resistant bacteria.
Cefuroxime axetil/clavulanic acid 500 mg/kg twice daily is more effective as amoxicillin 500 mg/kg three times daily in the treatment of pneuminia and produces fewer gastroinrestinal adverse effects,particulary diarrhea.
Cefuroxime/clavulanic acid,"follow-on" therapy produces clinical and bacteriological efficacy equivalent to that of amoxicillin/clavulanic acid,with the advantage to twice daily oral administration.
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